Design, synthesis, and biological evaluation of new 6,N(2)-diaryl-1,3,5-triazine-2,4-diamines as anticancer agents selectively targeting triple negative breast cancer cells

New 6,N(2)-diaryl-1,3,5-triazine-2,4-diamines were designed using the 3D-QSAR model developed earlier. These compounds were prepared and their antiproliferative activity was evaluated against three breast cancer cell lines (MDA-MB231, SKBR-3 and MCF-7) and non-cancerous MCF-10A epithelial breast cel...

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Detalles Bibliográficos
Autores principales: Junaid, Ahmad, Lim, Felicia Phei Lin, Tiekink, Edward R. T., Dolzhenko, Anton V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055250/
https://www.ncbi.nlm.nih.gov/pubmed/35518627
http://dx.doi.org/10.1039/d0ra04970k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055250/
https://www.ncbi.nlm.nih.gov/pubmed/35518627
http://dx.doi.org/10.1039/d0ra04970k

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