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miR-455-5p enhances 5-fluorouracil sensitivity in colorectal cancer cells by targeting PIK3R1 and DEPDC1

Our previous study has demonstrated that miR-455-5p was a tumor suppressor in colorectal cancer (CRC). This study aimed to investigate the role of miR-455-5p in 5-fluorouracil (5-Fu) in CRC. The expression of miR-455-5p, PIK3R1, and DEPDC1 was analyzed in HT-29 cells after treatment with different c...

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Detalles Bibliográficos
Autores principales: Lou, Tingting, Zhang, Luqing, Jin, Zongshan, Miao, Chundi, Wang, Jinqiu, Ke, Kongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055257/
https://www.ncbi.nlm.nih.gov/pubmed/35582195
http://dx.doi.org/10.1515/med-2022-0474