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Design, synthesis, biological evaluation and molecular docking study of novel pyridoxine–triazoles as anti-Alzheimer's agents

A series of multi-target natural product-pyridoxine based derivatives were designed, synthesized, characterized and evaluated as anti-Alzheimer agents. In vitro testing revealed the multi-functional properties of compounds such as inhibition of acetylcholinesterase (AChE), antioxidant and metal chel...

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Detalles Bibliográficos
Autores principales: Pal, Tiyas, Bhimaneni, Saipriyanka, Sharma, Abha, Flora, S. J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055346/
https://www.ncbi.nlm.nih.gov/pubmed/35519785
http://dx.doi.org/10.1039/d0ra04942e