High-affinity FcγRIIIa genetic variants and potent NK cell-mediated antibody-dependent cellular cytotoxicity (ADCC) responses contributing to severe COVID-19

PURPOSE: Host genetic variants in activating natural killer (NK) cell receptors may contribute to differences in severity of COVID-19. NK cell-mediated antibody-mediated cellular cytotoxicity (ADCC) responses play, however, a controversial role in SARS-CoV-2 infections. It is unclear whether proinfl...

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Detalles Bibliográficos
Autores principales: Vietzen, Hannes, Danklmaier, Vera, Zoufaly, Alexander, Puchhammer-Stöckl, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Medical Genetics and Genomics. Published by Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055393/
https://www.ncbi.nlm.nih.gov/pubmed/35488894
http://dx.doi.org/10.1016/j.gim.2022.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055393/
https://www.ncbi.nlm.nih.gov/pubmed/35488894
http://dx.doi.org/10.1016/j.gim.2022.04.005

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