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Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

The efforts towards developing a potential drug against the current global pandemic, COVID-19, have increased in the past few months. Drug development strategies to target the RNA dependent RNA polymerase (RdRP) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) are being tried worldwid...

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Detalles Bibliográficos
Autores principales: Koulgi, Shruti, Jani, Vinod, Uppuladinne, Mallikarjunachari V. N., Sonavane, Uddhavesh, Joshi, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055499/
https://www.ncbi.nlm.nih.gov/pubmed/35515752
http://dx.doi.org/10.1039/d0ra04743k