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Dual stimuli-responsive polyphosphazene-based molecular gates for controlled drug delivery in lung cancer cells

A switchable silane derived stimuli-responsive bottle-brush polyphosphazene (PPz) was prepared and attached to the surface of mesoporous silica nanoparticles (MSNs). The hybrid polymer with PEG-like Jeffamine® M-2005 side-arms undergo conformational changes in response to both pH and temperature due...

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Detalles Bibliográficos
Autores principales: Salinas, Yolanda, Kneidinger, Michael, Fornaguera, Cristina, Borrós, Salvador, Brüggemann, Oliver, Teasdale, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055533/
https://www.ncbi.nlm.nih.gov/pubmed/35516962
http://dx.doi.org/10.1039/d0ra03210g