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Retinal Neuroprotective Effect of Mesenchymal Stem Cells Secretome Through Modulation of Oxidative Stress, Autophagy, and Programmed Cell Death

PURPOSE: Degenerative mechanisms of retinal neurodegenerative diseases (RND) share common cellular and molecular signalization pathways. Curative treatment does not exist and cell-based therapy, through the paracrine properties of mesenchymal stem cells (MSC), is a potential unspecific treatment for...

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Detalles Bibliográficos
Autores principales: Usategui-Martín, Ricardo, Puertas-Neyra, Kevin, Galindo-Cabello, Nadia, Hernández-Rodríguez, Leticia A., González-Pérez, Fernando, Rodríguez-Cabello, José Carlos, González-Sarmiento, Rogelio, Pastor, José Carlos, Fernandez-Bueno, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055551/
https://www.ncbi.nlm.nih.gov/pubmed/35486068
http://dx.doi.org/10.1167/iovs.63.4.27