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Simple weak-acid derivatives of paclitaxel for remote loading into liposomes and improved therapeutic effects
Liposomes are among the most successful nanocarriers; several products have been marketed, all of which were prepared by active loading methods. However, poorly water-soluble drugs without ionizable groups are usually incorporated into the lipid bi-layer of liposomes by passive loading methods, with...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055615/ https://www.ncbi.nlm.nih.gov/pubmed/35516912 http://dx.doi.org/10.1039/d0ra03190a |