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Simple weak-acid derivatives of paclitaxel for remote loading into liposomes and improved therapeutic effects

Liposomes are among the most successful nanocarriers; several products have been marketed, all of which were prepared by active loading methods. However, poorly water-soluble drugs without ionizable groups are usually incorporated into the lipid bi-layer of liposomes by passive loading methods, with...

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Detalles Bibliográficos
Autores principales: Yu, Jiang, Zhou, Shuang, Li, Jinbo, Wang, Yingli, Su, Yujiao, Chi, Dongxu, Wang, Jiamei, Wang, Xue, He, Zhonggui, Lin, Guimei, Liu, Dan, Wang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055615/
https://www.ncbi.nlm.nih.gov/pubmed/35516912
http://dx.doi.org/10.1039/d0ra03190a