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Batch-effect detection, correction and characterisation in Illumina HumanMethylation450 and MethylationEPIC BeadChip array data

BACKGROUND: Genomic technologies can be subject to significant batch-effects which are known to reduce experimental power and to potentially create false positive results. The Illumina Infinium Methylation BeadChip is a popular technology choice for epigenome-wide association studies (EWAS), but pre...

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Detalles Bibliográficos
Autores principales: Ross, Jason P., van Dijk, Susan, Phang, Melinda, Skilton, Michael R., Molloy, Peter L., Oytam, Yalchin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055778/
https://www.ncbi.nlm.nih.gov/pubmed/35488315
http://dx.doi.org/10.1186/s13148-022-01277-9