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Preparation and characterisation of PHT-loaded chitosan lecithin nanoparticles for intranasal drug delivery to the brain

The use of nanoparticles (NPs) for intranasal (IN) drug delivery to the brain represents a hopeful strategy to enhance brain targeting of anti-epileptic drugs. In the present work, chitosan–lecithin NPs loaded with phenytoin (PHT), were prepared using the nano-precipitation method. The spherical nat...

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Detalles Bibliográficos
Autores principales: Yousfan, Amal, Rubio, Noelia, Natouf, Abdul Hakim, Daher, Aamal, Al-Kafry, Nedal, Venner, Kerrie, Kafa, Houmam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055806/
https://www.ncbi.nlm.nih.gov/pubmed/35520085
http://dx.doi.org/10.1039/d0ra04890a