PhieABEs: a PAM‐less/free high‐efficiency adenine base editor toolbox with wide target scope in plants

Adenine base editors (ABEs), which are generally engineered adenosine deaminases and Cas variants, introduce site‐specific A‐to‐G mutations for agronomic trait improvement. However, notably varying editing efficiencies, restrictive requirements for protospacer‐adjacent motifs (PAMs) and a narrow edi...

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Detalles Bibliográficos
Autores principales: Tan, Jiantao, Zeng, Dongchang, Zhao, Yanchang, Wang, Yaxi, Liu, Taoli, Li, Shuangchun, Xue, Yang, Luo, Yuyu, Xie, Xianrong, Chen, Letian, Liu, Yao‐Guang, Zhu, Qinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055815/
https://www.ncbi.nlm.nih.gov/pubmed/34984801
http://dx.doi.org/10.1111/pbi.13774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055815/
https://www.ncbi.nlm.nih.gov/pubmed/34984801
http://dx.doi.org/10.1111/pbi.13774

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