Cargando…

PhieABEs: a PAM‐less/free high‐efficiency adenine base editor toolbox with wide target scope in plants

Adenine base editors (ABEs), which are generally engineered adenosine deaminases and Cas variants, introduce site‐specific A‐to‐G mutations for agronomic trait improvement. However, notably varying editing efficiencies, restrictive requirements for protospacer‐adjacent motifs (PAMs) and a narrow edi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Jiantao, Zeng, Dongchang, Zhao, Yanchang, Wang, Yaxi, Liu, Taoli, Li, Shuangchun, Xue, Yang, Luo, Yuyu, Xie, Xianrong, Chen, Letian, Liu, Yao‐Guang, Zhu, Qinlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055815/ https://www.ncbi.nlm.nih.gov/pubmed/34984801 http://dx.doi.org/10.1111/pbi.13774

Ejemplares similares

Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum)
por: Wang, Guanying, et al.
Publicado: (2022)

Efficient assembly of long DNA fragments and multiple genes with improved nickase‐based cloning and Cre/ loxP recombination
por: Zhao, Yanchang, et al.
Publicado: (2022)

A Cas9 with PAM recognition for adenine dinucleotides
por: Chatterjee, Pranam, et al.
Publicado: (2020)

An Efficient Marker Gene Excision Strategy Based on CRISPR/Cas9-Mediated Homology-Directed Repair in Rice
por: Tan, Jiantao, et al.
Publicado: (2022)

Genome‐wide analyses of PAM‐relaxed Cas9 genome editors reveal substantial off‐target effects by ABE8e in rice
por: Wu, Yuechao, et al.
Publicado: (2022)

Efficient CRISPR/Cas9‐based plant genomic fragment deletions by microhomology‐mediated end joining
por: Tan, Jiantao, et al.
Publicado: (2020)

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation
por: Sheriff, Adam, et al.
Publicado: (2022)

[Abe Lincoln]
por: Ostendorf, Lloyd
Publicado: (1972)

Development of a high-fidelity Cas9-dependent adenine base editor (ABE) system for genome editing with high-fidelity Cas9 variants
por: Hong, Ruisha, et al.
Publicado: (2022)

Methods for Leveraging a Health Information Exchange for Public Health: Lessons Learned from the NW-PHIE Experience
por: Trebatoski, M, et al.
Publicado: (2010)

Quantitative regulation of Waxy expression by CRISPR/Cas9‐based promoter and 5'UTR‐intron editing improves grain quality in rice
por: Zeng, Dongchang, et al.
Publicado: (2020)

¿ABCDerio o ABeCeDamo?
por: Leyva, Daniel
Publicado: (1980)

Disease modeling by efficient genome editing using a near PAM-less base editor in vivo
por: Rosello, Marion, et al.
Publicado: (2022)

ABE8e with Polycistronic tRNA-gRNA Expression Cassette Sig-Nificantly Improves Adenine Base Editing Efficiency in Nicotiana benthamiana
por: Wang, Zupeng, et al.
Publicado: (2021)

Engineered prime editors with PAM flexibility
por: Kweon, Jiyeon, et al.
Publicado: (2021)

Exploring C-to-G and A-to-Y Base Editing in Rice by Using New Vector Tools
por: Zeng, Dongchang, et al.
Publicado: (2022)

A Tribute to Abe Mickal, 1912–2001
por: Faro, Sebastian
Publicado: (2001)

Analysis of an ABE Scheme with Verifiable Outsourced Decryption
por: Liao, Yongjian, et al.
Publicado: (2018)

Applied in situ product recovery in ABE fermentation
por: Outram, Victoria, et al.
Publicado: (2017)

Plant Synthetic Metabolic Engineering for Enhancing Crop Nutritional Quality
por: Zhu, Qinlong, et al.
Publicado: (2019)

Combining Experimentation and Theory: A Hommage to Abe Mamdani
por: Trillas, Enric, et al.
Publicado: (2012)

Unlocking the secrets of ABEs: the molecular mechanism behind their specificity
por: Chen, Xiaoyu, et al.
Publicado: (2023)

BEtarget: A versatile web-based tool to design guide RNAs for base editing in plants
por: Xie, Xianrong, et al.
Publicado: (2022)

Prospects and progress on crocin biosynthetic pathway and metabolic engineering
por: Liu, Taoli, et al.
Publicado: (2020)

Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants
por: Xin, Huhu, et al.
Publicado: (2019)

All‐in‐one: a robust fluorescent fusion protein vector toolbox for protein localization and BiFC analyses in plants
por: Han, Jingluan, et al.
Publicado: (2022)

Simplified adenine base editors improve adenine base editing efficiency in rice
por: Hua, Kai, et al.
Publicado: (2019)

ABE-VIEW: Android Interface for Wireless Data Acquisition and Control
por: Jenkins, Daniel M., et al.
Publicado: (2018)

Complete genome sequence of new bacteriophage phiE142, which causes simultaneously lysis of multidrug-resistant Escherichia coli O157:H7 and Salmonella enterica
por: Amarillas, Luis, et al.
Publicado: (2016)

Nicking Endonuclease-Mediated Vector Construction Strategies for Plant Gene Functional Research
por: Gong, Qi, et al.
Publicado: (2020)

Online/Offline MA-CP-ABE with Cryptographic Reverse Firewalls for IoT
por: Li, Juyan, et al.
Publicado: (2023)

Highly Efficient A-to-G Editing in PFFs via Multiple ABEs
por: Jing, Qiqi, et al.
Publicado: (2023)

Engineered Cas9 variant tools expand targeting scope of genome and base editing in rice
por: Zeng, Dongchang, et al.
Publicado: (2019)

Toolbox for Mobile-Element Insertion Detection on Cancer Genomes
por: Lee, Wan-Ping, et al.
Publicado: (2014)

Toolbox for Mobile-Element Insertion Detection on Cancer Genomes
por: Lee, Wan-Ping, et al.
Publicado: (2015)

The LEPSIS Pam-File
por: DELPHI Collaboration
Publicado: (1982)

Haemopoietic progenitor-cell responses in mice with the transplanted lymphoid leukaemia ABE-8.
por: McCarthy, J. H.
Publicado: (1979)

Highly efficient A-to-G base editing by ABE8.17 in rabbits
por: Zhao, Ding, et al.
Publicado: (2022)

Detection of Protein Palmitoylation in Cultured Hippocampal Neurons by Immunoprecipitation and Acyl-Biotin Exchange (ABE)
por: Brigidi, G. Stefano, et al.
Publicado: (2013)

The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies
por: Rasetti-Escargueil, Christine, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_dnd8thkn1lv0gqf9an7l29ohdj