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scMAPA: Identification of cell-type–specific alternative polyadenylation in complex tissues

BACKGROUND: Alternative polyadenylation (APA) causes shortening or lengthening of the 3ʹ-untranslated region (3ʹ-UTR) of genes (APA genes) in diverse cellular processes such as cell proliferation and differentiation. To identify cell-type–specific APA genes in scRNA-Seq data, current bioinformatic m...

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Detalles Bibliográficos
Autores principales: Bai, Yulong, Qin, Yidi, Fan, Zhenjiang, Morrison, Robert M, Nam, KyongNyon, Zarour, Hassane M, Koldamova, Radosveta, Padiath, Quasar Saleem, Kim, Soyeon, Park, Hyun Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055853/
https://www.ncbi.nlm.nih.gov/pubmed/35488860
http://dx.doi.org/10.1093/gigascience/giac033