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Accelerated trypsin autolysis by affinity polymer templates

Self-cleavage of proteins is an important natural process that is difficult to control externally. Recently a new mechanism for the accelerated autolysis of trypsin was discovered involving polyanionic template polymers; however it relies on unspecific interactions and is inactive at elevated salt l...

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Detalles Bibliográficos
Autores principales: Smolin, Daniel, Tötsch, Niklas, Grad, Jean-Noël, Linders, Jürgen, Kaschani, Farnusch, Kaiser, Markus, Kirsch, Michael, Hoffmann, Daniel, Schrader, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055874/
https://www.ncbi.nlm.nih.gov/pubmed/35520047
http://dx.doi.org/10.1039/d0ra05827k