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The construction of the novel magnetic prodrug Fe(3)O(4)@DOX and its antagonistic effects on hepatocarcinoma with low toxicity

Doxorubicin (DOX) is widely used as a chemotherapeutic agent for liver cancer. However, its clinical applications are greatly restricted by its nonselective cytotoxicity. A novel magnetic prodrug, Fe(3)O(4)@DOX, was designed, synthesized and characterized, and Fe(3)O(4) and DOX were connected by the...

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Detalles Bibliográficos
Autores principales: Li, Jun, Li, Liang, Lv, Yang, Zou, Hao, Wei, Yanping, Nie, Fei, Duan, Wanli, Sedike, Maidinamu, Xiao, Liang, Wang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055880/
https://www.ncbi.nlm.nih.gov/pubmed/35520056
http://dx.doi.org/10.1039/d0ra01729a