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Genome‐scale screening in a rat haploid system identifies Thop1 as a modulator of pluripotency exit
OBJECTIVES: The rats are crucial animal models for the basic medical researches. Rat embryonic stem cells (ESCs), which are widely studied, can self‐renew and exhibit pluripotency in long‐term culture, but the mechanism underlying how they exit pluripotency remains obscure. To investigate the key mo...
Autores principales: | Xu, Mei, Zhao, Yiding, Zhang, Wenhao, Geng, Mengyang, Liu, Qian, Gao, Qian, Shuai, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055895/ https://www.ncbi.nlm.nih.gov/pubmed/35274380 http://dx.doi.org/10.1111/cpr.13209 |
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