α-Glucosidase inhibitors from Chinese bayberry (Morella rubra Sieb. et Zucc.) fruit: molecular docking and interaction mechanism of flavonols with different B-ring hydroxylations

Inhibition of α-glucosidase alleviates postprandial high glycemic levels in diabetic or prediabetic population. In Chinese bayberry fruit, myricetin, quercetin and kaempferol are main flavonols, which differ only in their hydroxylation on the B-ring. Kaempferol (4′-OH) showed high IC(50) (65.36 ± 0....

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Detalles Bibliográficos
Autores principales: Liu, Yilong, Zhan, Liuhuan, Xu, Chang, Jiang, Huamin, Zhu, Changqing, Sun, Linxiao, Sun, Chongde, Li, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055920/
https://www.ncbi.nlm.nih.gov/pubmed/35521141
http://dx.doi.org/10.1039/d0ra05015f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055920/
https://www.ncbi.nlm.nih.gov/pubmed/35521141
http://dx.doi.org/10.1039/d0ra05015f

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