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Multi-enzyme pyruvate removal system to enhance (R)-selective reductive amination of ketones

Biocatalytic transamination is widely used in industrial production of chiral chemicals. Here, we constructed a novel multi-enzyme system to promote the conversion of the amination reaction. Firstly, we constructed the ArR-ωTA/TdcE/FDH/LDH multi-enzyme system, by combination of (R)-selective ω-trans...

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Detalles Bibliográficos
Autores principales: Zhang, Jinhua, Zhao, Yanshu, Li, Chao, Song, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055928/
https://www.ncbi.nlm.nih.gov/pubmed/35520080
http://dx.doi.org/10.1039/d0ra06140a