Manifold of self-assembly of a de novo designed peptide: amyloid fibrils, peptide bundles, and fractals

We report that a peptide with the sequence of EGAGAAAAGAGE can have different aggregation states, viz., amyloid fibrils, peptide bundles, and fractal assembly under different incubation conditions. The chemical state of the Glu residue played a pivotal regulating role in the aggregation behavior of...

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Detalles Bibliográficos
Autores principales: Chao, Yu-Jo, Wu, Kan, Chang, Hsun-Hui, Chien, Ming-Jou, Chan, Jerry Chun Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055936/
https://www.ncbi.nlm.nih.gov/pubmed/35521097
http://dx.doi.org/10.1039/d0ra04480f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055936/
https://www.ncbi.nlm.nih.gov/pubmed/35521097
http://dx.doi.org/10.1039/d0ra04480f

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