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Copper-catalyzed synthesis of α-ketoamides using water and dioxygen as the oxygen source
The reaction employing H(2)O and O(2) as the co-oxygen source in the catalytic synthesis of α-ketoamides is described. This copper-catalyzed reaction is carried out in a tandem manner constituted by the hydroamination of alkyne, hydration of vinyl–Cu complex and subsequent oxidation. Isotope labelin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055944/ https://www.ncbi.nlm.nih.gov/pubmed/35521140 http://dx.doi.org/10.1039/d0ra05921h |