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Copper-catalyzed synthesis of α-ketoamides using water and dioxygen as the oxygen source

The reaction employing H(2)O and O(2) as the co-oxygen source in the catalytic synthesis of α-ketoamides is described. This copper-catalyzed reaction is carried out in a tandem manner constituted by the hydroamination of alkyne, hydration of vinyl–Cu complex and subsequent oxidation. Isotope labelin...

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Detalles Bibliográficos
Autores principales: Xiao, Yuanyuan, Yi, Zijuan, Yu, Xianyong, Xiao, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055944/
https://www.ncbi.nlm.nih.gov/pubmed/35521140
http://dx.doi.org/10.1039/d0ra05921h