Transition-metal and oxidant-free approach for the synthesis of diverse N-heterocycles by TMSCl activation of isocyanides

A highly efficient TMSCl-mediated addition of N-nucleophiles to isocyanides has been achieved. This transition-metal and oxidant-free strategy has been applied to the construction of various N-heterocyles such as quinazolinone, benzimidazole and benzothiazole derivatives by the use of distinct amino...

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Detalles Bibliográficos
Autores principales: Luo, Liangliang, Li, Hongyan, Liu, Jinxin, Zhou, Yuan, Dong, Lin, Xiao, You-Cai, Chen, Fen-Er
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055958/
https://www.ncbi.nlm.nih.gov/pubmed/35521093
http://dx.doi.org/10.1039/d0ra04636a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055958/
https://www.ncbi.nlm.nih.gov/pubmed/35521093
http://dx.doi.org/10.1039/d0ra04636a

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