Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells

In this work, gallium(III) complex with cloxyquin (5-chloro-8-quinolinol, HClQ) ligands is shown to effectively inhibit proliferation of rhabdomyosarcoma cells, the frequent, aggressive, and poorly treatable cancer of children. It offers striking selectivity to cancer cells compared to noncancerous...

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Detalles Bibliográficos
Autores principales: Hreusova, Monika, Novohradsky, Vojtech, Markova, Lenka, Kostrhunova, Hana, Potočňák, Ivan, Brabec, Viktor, Kasparkova, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056256/
https://www.ncbi.nlm.nih.gov/pubmed/35502218
http://dx.doi.org/10.1155/2022/3095749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056256/
https://www.ncbi.nlm.nih.gov/pubmed/35502218
http://dx.doi.org/10.1155/2022/3095749

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