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Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells
In this work, gallium(III) complex with cloxyquin (5-chloro-8-quinolinol, HClQ) ligands is shown to effectively inhibit proliferation of rhabdomyosarcoma cells, the frequent, aggressive, and poorly treatable cancer of children. It offers striking selectivity to cancer cells compared to noncancerous...
Autores principales: | Hreusova, Monika, Novohradsky, Vojtech, Markova, Lenka, Kostrhunova, Hana, Potočňák, Ivan, Brabec, Viktor, Kasparkova, Jana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056256/ https://www.ncbi.nlm.nih.gov/pubmed/35502218 http://dx.doi.org/10.1155/2022/3095749 |
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