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A [3 + 2] cycloaddition/C-arylation of isatin N,N′-cyclic azomethine imine 1,3-dipole with arynes

A [3 + 2] annulation/C-arylation of isatin N,N′-cyclic azomethine imine 1,3-dipole 1 with in situ generated arynes has been established for the synthesis of 3,3-disubstituted oxindole scaffolds. These highly functionalized scaffolds were assembled in moderate yields (up to 85% yield). The novel spir...

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Detalles Bibliográficos
Autores principales: Jin, Qiaomei, Zhang, Dongjian, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056323/
https://www.ncbi.nlm.nih.gov/pubmed/35516012
http://dx.doi.org/10.1039/d0ra06404a