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Probing intrinsic dynamics and conformational transition of HIV gp120 by molecular dynamics simulation
The HIV envelope glycoprotein gp120 has evolved two distinct conformational states to balance viral infection and immune escape. One is a closed state resistant to most neutralization antibodies, and the other is an open state responsible for the binding of the receptor and coreceptors. Although the...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056330/ https://www.ncbi.nlm.nih.gov/pubmed/35516019 http://dx.doi.org/10.1039/d0ra06416e |