Cargando…
Synthesis of 1,3,4-oxadiazoles derivatives with antidepressant activity and their binding to the 5-HT(1A) receptor
In this study, two series of 1,3,4-oxadiazole derivatives were designed and synthesized using the forced swimming test (FST) model to test the antidepressant activity of the target compound in vivo. Five compounds with potential activity were selected from the FST model to test affinity with 5-HT(1A...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056355/ https://www.ncbi.nlm.nih.gov/pubmed/35516063 http://dx.doi.org/10.1039/d0ra05886f |