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Synthesis of 1,3,4-oxadiazoles derivatives with antidepressant activity and their binding to the 5-HT(1A) receptor

In this study, two series of 1,3,4-oxadiazole derivatives were designed and synthesized using the forced swimming test (FST) model to test the antidepressant activity of the target compound in vivo. Five compounds with potential activity were selected from the FST model to test affinity with 5-HT(1A...

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Detalles Bibliográficos
Autores principales:	Wang, Shiben, Qi, Lin, Liu, Hui, Lei, Kang, Wang, Xuekun, Liu, Renmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056355/ https://www.ncbi.nlm.nih.gov/pubmed/35516063 http://dx.doi.org/10.1039/d0ra05886f

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