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New marine-derived indolymethyl pyrazinoquinazoline alkaloids with promising antimicrobial profiles

Due to the emergence of multidrug-resistant pathogenic microorganisms, the search for novel antimicrobials is urgent. Inspired by marine alkaloids, a series of indolomethyl pyrazino [1,2-b]quinazoline-3,6-diones was prepared using a one-pot microwave-assisted multicomponent polycondensation of amino...

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Detalles Bibliográficos
Autores principales: Long, Solida, Resende, Diana I. S. P., Palmeira, Andreia, Kijjoa, Anake, Silva, Artur M. S., Tiritan, Maria Elizabeth, Pereira-Terra, Patrícia, Freitas-Silva, Joana, Barreiro, Sandra, Silva, Renata, Remião, Fernando, Pinto, Eugénia, Martins da Costa, Paulo, Sousa, Emília, Pinto, Madalena M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056383/
https://www.ncbi.nlm.nih.gov/pubmed/35520644
http://dx.doi.org/10.1039/d0ra05319h