Discovery of mercaptopropanamide-substituted aryl tetrazoles as new broad-spectrum metallo-β-lactamase inhibitors

β-Lactam antibiotic resistance mediated by metallo-β-lactamases (MBL) has threatened global public health. There are currently no available inhibitors of MBLs for clinical use. We previously reported the ruthenium-catalyzed meta-selective C–H nitration synthesis method, leading to some meta-mercapto...

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Detalles Bibliográficos
Autores principales: Yan, Yu-Hang, Chen, Jian, Zhan, Zhen, Yu, Zhu-Jun, Li, Gen, Guo, Li, Li, Guo-Bo, Wu, Yong, Zheng, Yongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056430/
https://www.ncbi.nlm.nih.gov/pubmed/35520685
http://dx.doi.org/10.1039/d0ra06405j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056430/
https://www.ncbi.nlm.nih.gov/pubmed/35520685
http://dx.doi.org/10.1039/d0ra06405j

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