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Mutational spectrum of hepatitis C virus in patients with chronic hepatitis C determined by single molecule real-time sequencing
The emergence of hepatitis C virus (HCV) with resistance-associated substitution (RAS), produced by mutations in the HCV genome, is a major problem in direct acting antivirals (DAA) treatment. This study aimed to clarify the mutational spectrum in HCV-RNA and the substitution pattern for the emergen...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056513/ https://www.ncbi.nlm.nih.gov/pubmed/35490163 http://dx.doi.org/10.1038/s41598-022-11151-6 |