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Mutational spectrum of hepatitis C virus in patients with chronic hepatitis C determined by single molecule real-time sequencing

The emergence of hepatitis C virus (HCV) with resistance-associated substitution (RAS), produced by mutations in the HCV genome, is a major problem in direct acting antivirals (DAA) treatment. This study aimed to clarify the mutational spectrum in HCV-RNA and the substitution pattern for the emergen...

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Detalles Bibliográficos
Autores principales:	Nakamura, Fumiyasu, Takeda, Haruhiko, Ueda, Yoshihide, Takai, Atsushi, Takahashi, Ken, Eso, Yuji, Arasawa, Soichi, Iguchi, Eriko, Shimizu, Takahiro, Mishima, Masako, Kumagai, Ken, Yamashita, Taiki, Uemoto, Shinji, Kato, Nobuyuki, Marusawa, Hiroyuki, Sekine, Akihiro, Seno, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056513/ https://www.ncbi.nlm.nih.gov/pubmed/35490163 http://dx.doi.org/10.1038/s41598-022-11151-6

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