Molecular dynamics simulations of the secondary-binding site in disaccharide-modified glycopeptide antibiotics

Oritavancin is a semisynthetic glycopeptide antibiotic used to treat severe infections by multidrug-resistant Gram-positive pathogens. Oritavancin is known to be a thousand times more potent than vancomycin against Gram-positive bacteria due to the additional interactions with bacterial peptidoglyca...

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Detalles Bibliográficos
Autores principales: Olademehin, Olatunde P., Shuford, Kevin L., Kim, Sung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056522/
https://www.ncbi.nlm.nih.gov/pubmed/35490171
http://dx.doi.org/10.1038/s41598-022-10735-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056522/
https://www.ncbi.nlm.nih.gov/pubmed/35490171
http://dx.doi.org/10.1038/s41598-022-10735-6

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