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Reporter-recruiting bifunctional aptasensor for bioluminescent analytical assays
We report a novel bioluminescent aptasensor, which consists of 2′-F-RNA aptamer modules joined into a bi-specific aptamer construct. One aptamer module binds the analyte, then after structural rearrangement the second module recruits non-covalently Ca(2+)-dependent photoprotein obelin from the solut...
Main Authors: | , , , , , , , , |
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Format: | Online Article Text |
Language: | English |
Published: |
The Royal Society of Chemistry
2020
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Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056652/ https://www.ncbi.nlm.nih.gov/pubmed/35516485 http://dx.doi.org/10.1039/d0ra05117a |