Reporter-recruiting bifunctional aptasensor for bioluminescent analytical assays

We report a novel bioluminescent aptasensor, which consists of 2′-F-RNA aptamer modules joined into a bi-specific aptamer construct. One aptamer module binds the analyte, then after structural rearrangement the second module recruits non-covalently Ca(2+)-dependent photoprotein obelin from the solut...

Descripción completa

Detalles Bibliográficos
Autores principales: Davydova, Anna, Krasitskaya, Vasilisa, Vorobjev, Pavel, Timoshenko, Valentina, Tupikin, Alexey, Kabilov, Marsel, Frank, Ludmila, Venyaminova, Alya, Vorobyeva, Mariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056652/
https://www.ncbi.nlm.nih.gov/pubmed/35516485
http://dx.doi.org/10.1039/d0ra05117a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056652/
https://www.ncbi.nlm.nih.gov/pubmed/35516485
http://dx.doi.org/10.1039/d0ra05117a

Ejemplares similares