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Reporter-recruiting bifunctional aptasensor for bioluminescent analytical assays

We report a novel bioluminescent aptasensor, which consists of 2′-F-RNA aptamer modules joined into a bi-specific aptamer construct. One aptamer module binds the analyte, then after structural rearrangement the second module recruits non-covalently Ca(2+)-dependent photoprotein obelin from the solut...

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Detalles Bibliográficos
Autores principales:	Davydova, Anna, Krasitskaya, Vasilisa, Vorobjev, Pavel, Timoshenko, Valentina, Tupikin, Alexey, Kabilov, Marsel, Frank, Ludmila, Venyaminova, Alya, Vorobyeva, Mariya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056652/ https://www.ncbi.nlm.nih.gov/pubmed/35516485 http://dx.doi.org/10.1039/d0ra05117a

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