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Preactivated-thiolated polyacrylic acid/1-vinyl pyrrolidone nanoparticles as nicotine carriers for smoking cessation

This study aimed to develop nicotine-loaded mucoadhesive preactivated-thiolated polymeric nanoparticles (PNPs) for smoking cessation. 2-Mercaptonicotinic acid (2MNA) was coupled as dithionicotinic acid dimer and used in the preactivation of thiolated polyacrylic acid/vinyl pyrrolidone PNPs (thiolate...

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Detalles Bibliográficos
Autores principales: Pornpitchanarong, Chaiyakarn, Rojanarata, Theerasak, Opanasopit, Praneet, Ngawhirunpat, Tanasait, Patrojanasophon, Prasopchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056685/
https://www.ncbi.nlm.nih.gov/pubmed/35515031
http://dx.doi.org/10.1039/d0ra06039a