NMR-based quantitative studies of the conformational equilibrium between their square and folded forms of ascidiacyclamide and its analogues

Ascidiacyclamide [cyclo(-Ile(1,5)-oxazoline(2,6)-D-Val(3,7)-thiazole(4,8)-)] (1) is a cytotoxic cyclic peptide from the ascidian, or sea squirt. Through structural analyses using asymmetric analogues [Xxx(1): Ala (2), Val (3), Leu (4), Phe (5), cyclohexylalanine (6) and phenylglycine (7)], we previo...

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Detalles Bibliográficos
Autores principales: Asano, Akiko, Minoura, Katsuhiko, Kojima, Yuki, Yoshii, Taishi, Ito, Ryoya, Yamada, Takeshi, Kato, Takuma, Doi, Mitsunobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056700/
https://www.ncbi.nlm.nih.gov/pubmed/35515040
http://dx.doi.org/10.1039/d0ra07396b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056700/
https://www.ncbi.nlm.nih.gov/pubmed/35515040
http://dx.doi.org/10.1039/d0ra07396b

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