Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH(4)SCN and N-thiosuccinimides

A highly regioselective thiocyanatothiolation of alkynes and alkenes assisted by hydrogen bonding under simple and mild conditions is developed. Our thiocyanatothiolation reagents are readily available ammonium thiocyanate and N-thiosuccinimides. This metal-free system offers good chemical yields fo...

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Detalles Bibliográficos
Autores principales: Qi, Liang, Liu, Shiwen, Xiao, Linxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056709/
https://www.ncbi.nlm.nih.gov/pubmed/35515071
http://dx.doi.org/10.1039/d0ra06913b
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author Qi, Liang
Liu, Shiwen
Xiao, Linxia
author_facet Qi, Liang
Liu, Shiwen
Xiao, Linxia
author_sort Qi, Liang
collection PubMed
description A highly regioselective thiocyanatothiolation of alkynes and alkenes assisted by hydrogen bonding under simple and mild conditions is developed. Our thiocyanatothiolation reagents are readily available ammonium thiocyanate and N-thiosuccinimides. This metal-free system offers good chemical yields for a wide range of alkyne and alkene substrates with good functional group tolerance.
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spelling pubmed-90567092022-05-04 Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH(4)SCN and N-thiosuccinimides Qi, Liang Liu, Shiwen Xiao, Linxia RSC Adv Chemistry A highly regioselective thiocyanatothiolation of alkynes and alkenes assisted by hydrogen bonding under simple and mild conditions is developed. Our thiocyanatothiolation reagents are readily available ammonium thiocyanate and N-thiosuccinimides. This metal-free system offers good chemical yields for a wide range of alkyne and alkene substrates with good functional group tolerance. The Royal Society of Chemistry 2020-09-10 /pmc/articles/PMC9056709/ /pubmed/35515071 http://dx.doi.org/10.1039/d0ra06913b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Qi, Liang
Liu, Shiwen
Xiao, Linxia
Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH(4)SCN and N-thiosuccinimides
title Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH(4)SCN and N-thiosuccinimides
title_full Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH(4)SCN and N-thiosuccinimides
title_fullStr Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH(4)SCN and N-thiosuccinimides
title_full_unstemmed Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH(4)SCN and N-thiosuccinimides
title_short Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH(4)SCN and N-thiosuccinimides
title_sort regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using nh(4)scn and n-thiosuccinimides
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056709/
https://www.ncbi.nlm.nih.gov/pubmed/35515071
http://dx.doi.org/10.1039/d0ra06913b
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AT liushiwen regioandstereoselectivethiocyanatothiolationofalkynesandalkenesbyusingnh4scnandnthiosuccinimides
AT xiaolinxia regioandstereoselectivethiocyanatothiolationofalkynesandalkenesbyusingnh4scnandnthiosuccinimides

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