Synthesis, biological evaluation, and in silico studies of novel chalcone- and pyrazoline-based 1,3,5-triazines as potential anticancer agents

A novel series of triazin-chalcones (7,8)a–g and triazin-N-(3,5-dichlorophenyl)pyrazolines (9,10)a–g were synthesized and evaluated for their anticancer activity against nine different cancer strains. Triazine ketones 5 and 6 were synthesized from the cyanuric chloride 1 by using stepwise nucleophil...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreno, Leydi M., Quiroga, Jairo, Abonia, Rodrigo, Lauria, Antonino, Martorana, Annamaria, Insuasty, Henry, Insuasty, Braulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056798/
https://www.ncbi.nlm.nih.gov/pubmed/35519030
http://dx.doi.org/10.1039/d0ra06799g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056798/
https://www.ncbi.nlm.nih.gov/pubmed/35519030
http://dx.doi.org/10.1039/d0ra06799g

Ejemplares similares