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Synthesis, biological evaluation, and in silico studies of novel chalcone- and pyrazoline-based 1,3,5-triazines as potential anticancer agents

A novel series of triazin-chalcones (7,8)a–g and triazin-N-(3,5-dichlorophenyl)pyrazolines (9,10)a–g were synthesized and evaluated for their anticancer activity against nine different cancer strains. Triazine ketones 5 and 6 were synthesized from the cyanuric chloride 1 by using stepwise nucleophil...

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Detalles Bibliográficos
Autores principales:	Moreno, Leydi M., Quiroga, Jairo, Abonia, Rodrigo, Lauria, Antonino, Martorana, Annamaria, Insuasty, Henry, Insuasty, Braulio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056798/ https://www.ncbi.nlm.nih.gov/pubmed/35519030 http://dx.doi.org/10.1039/d0ra06799g

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