Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

The 2019 coronavirus (COVID-19) pandemic is spreading worldwide, with a dramatic increase in death without any effective therapeutic treatment available up to now. We previously reported quinazoline-trihydroxyphenyl Schiff base conjugates as phosphodiesterase 4B (PDE 4B) inhibitors (an enzyme that p...

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Detalles Bibliográficos
Autores principales: Mansour, Mostafa A., AboulMagd, Asmaa M., Abdel-Rahman, Hamdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056799/
https://www.ncbi.nlm.nih.gov/pubmed/35519053
http://dx.doi.org/10.1039/d0ra06424f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056799/
https://www.ncbi.nlm.nih.gov/pubmed/35519053
http://dx.doi.org/10.1039/d0ra06424f

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