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Potential metabolism determinants and drug–drug interactions of a natural flavanone bavachinin

Bavachinin, a natural bioactive flavanone, is reported to have many pharmacological proprieties, especially anti-osteoporosis activity. Here we aim to determine the roles of cytochrome P450s (CYP), UDP-glucuronosyltransferases (UGT), and efflux transporters in metabolism and drug–drug interactions (...

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Detalles Bibliográficos
Autores principales: Li, Xinqiang, Xing, Han, Qin, Zifei, Yang, Jing, Wang, Peile, Zhang, Xiaojian, Yao, Zhihong, Yao, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056855/
https://www.ncbi.nlm.nih.gov/pubmed/35515695
http://dx.doi.org/10.1039/d0ra06961b