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Study on mechanism of elemene reversing tumor multidrug resistance based on luminescence pharmacokinetics in tumor cells in vitro and in vivo

While elemene (ELE) can reverse tumor multidrug resistance (MDR), the mechanisms for ELE reversing MDR remain unclear. Numerous studies have suggested that the efflux functionality of ATP-binding cassette (ABC) transporters, not their quantity, is more relevant to tumor MDR. However, no appropriate...

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Detalles Bibliográficos
Autores principales: Chen, Liying, Chen, Zhi, Zheng, Shuang, Fan, Luhui, Zhu, Lixin, Yu, Jiandong, Tang, Chaoyuan, Liu, Qi, Xiong, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056898/
https://www.ncbi.nlm.nih.gov/pubmed/35514396
http://dx.doi.org/10.1039/d0ra00184h