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A first-principles study on potential chelation agents and indicators of Alzheimer's disease

Human-serum transferrin is involved in the transportation of aluminum across the blood–brain barrier. Aluminum accumulation within the neuron causes the cell to degrade. In our research, we considered 12 potential chelators of aluminum from the aluminum–human serum transferrin complex and 3 potentia...

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Detalles Bibliográficos
Autores principales: Wang, Bryan, Luo, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056942/
https://www.ncbi.nlm.nih.gov/pubmed/35515673
http://dx.doi.org/10.1039/d0ra06855a