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Synthesis and biochemical evaluation of cephalosporin analogues equipped with chemical tethers

Molecular probes typically require structural modifications to allow for the immobilisation or bioconjugation with a desired substrate but the effects of these changes are often not evaluated. Here, we set out to determine the effects of attaching functional handles to a first-generation cephalospor...

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Detalles Bibliográficos
Autores principales: Miller, Lisa M., Herman, Reyme, Gyulev, Ivan, Krauss, Thomas F., Thomas, Gavin H., Duhme-Klair, Anne-Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056950/
https://www.ncbi.nlm.nih.gov/pubmed/35517937
http://dx.doi.org/10.1039/d0ra04893c