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Grafting of anti-nucleolin aptamer into preformed and remotely loaded liposomes through aptamer-cholesterol post-insertion

A new combination strategy of an active loading and active targeting approach was applied in this work. The liposomes actively loaded with Curcumin (CRM) (Lip(CRM)) were decorated with cholesterol tagged-anti-nucleolin AS1411 aptamer (NCL) via a new post-insertion approach, utilizing the cholesterol...

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Detalles Bibliográficos
Autores principales: Nsairat, Hamdi, Mahmoud, Ismail S., Odeh, Fadwa, Abuarqoub, Duaa, Al-Azzawi, Hafsa, Zaza, Rand, Qadri, Malak I., Ismail, Said, Al Bawab, Abeer, Awidi, Abdalla, Alshaer, Walhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056972/
https://www.ncbi.nlm.nih.gov/pubmed/35517091
http://dx.doi.org/10.1039/d0ra07325c