Investigation of some benzoquinazoline and quinazoline derivatives as novel inhibitors of HCV-NS3/4A protease: biological, molecular docking and QSAR studies

Morbidity and mortality due to hepatitis C virus (HCV) is a globe health concern. Hence, there is a persistent demand to design and optimize current HCV therapy and develop novel agents. HCV NS3/A4 protease plays an essential role in HCV life cycle and replication. Thus, HCV NS3/A4 protease inhibito...

Descripción completa

Detalles Bibliográficos
Autores principales: Abuelizz, Hatem A., Marzouk, Mohamed, Bakheit, Ahmed H., Al-Salahi, Rashad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056986/
https://www.ncbi.nlm.nih.gov/pubmed/35517076
http://dx.doi.org/10.1039/d0ra05604a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056986/
https://www.ncbi.nlm.nih.gov/pubmed/35517076
http://dx.doi.org/10.1039/d0ra05604a

Ejemplares similares