Synthesis of chiral 1,4-oxazepane-5-carboxylic acids from polymer-supported homoserine

The preparation of novel 1,4-oxazepane-5-carboxylic acids bearing two stereocenters is reported in this article. Fmoc-HSe(TBDMS)-OH immobilized on Wang resin was reacted with different nitrobenzenesulfonyl chlorides and alkylated with 2-bromoacetophenones to yield N-phenacyl nitrobenzenesulfonamides...

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Detalles Bibliográficos
Autores principales: Králová, Petra, Lemrová, Barbora, Maloň, Michal, Soural, Miroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056997/
https://www.ncbi.nlm.nih.gov/pubmed/35517075
http://dx.doi.org/10.1039/d0ra07997a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056997/
https://www.ncbi.nlm.nih.gov/pubmed/35517075
http://dx.doi.org/10.1039/d0ra07997a

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