Simultaneous estimation of dimenhydrinate, cinnarizine and their toxic impurities benzophenone and diphenylmethylpiperazine; in silico toxicity profiling of impurities

The British Pharmacopeia (BP) reported that the carcinogenic and hepatotoxic, benzophenone (BZP) is a dimenhydrinate (DMH) impurity. On the other hand, cinnarizine (CIN) is reported to have five impurities (A–E). The toxicity profile of CIN impurities was studied and the in silico data revealed that...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdelwahab, Nada S., Edrees, Fadwa H., Alsaadi, Mohammed T., Amin, Noha H., Saad, Ahmed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057124/
https://www.ncbi.nlm.nih.gov/pubmed/35521250
http://dx.doi.org/10.1039/d0ra06147f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057124/
https://www.ncbi.nlm.nih.gov/pubmed/35521250
http://dx.doi.org/10.1039/d0ra06147f

Ejemplares similares