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Recent advances in the development of histone deacylase SIRT2 inhibitors

Sirtuin 2 (SIRT2) is an important and special member of the atypical histone deacetylase Sirtuin (SIRT) family. Due to its extensive catalytic effects, SIRT2 can regulate autophagy, myelination, immunity, inflammation and other physiological processes. Recent evidence revealed that dysregulation of...

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Detalles Bibliográficos
Autores principales: Yang, Wenyu, Chen, Wei, Su, Huilin, Li, Rong, Song, Chen, Wang, Zhouyu, Yang, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057128/
https://www.ncbi.nlm.nih.gov/pubmed/35521274
http://dx.doi.org/10.1039/d0ra06316a