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α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction

A metal-free and efficient procedure for the synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and indolo[1,2-a]quinoxaline has been developed. The key features of our method include the in situ generation of aldehyde from α-hydroxy acid in the presence of TBHP (tert-butyl hydrogen peroxide),...

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Detalles Bibliográficos
Autores principales: Viji, Mayavan, Vishwanath, Manjunatha, Sim, Jaeuk, Park, Yunjeong, Jung, Chanhyun, Lee, Seohu, Lee, Heesoon, Lee, Kiho, Jung, Jae-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057147/
https://www.ncbi.nlm.nih.gov/pubmed/35521290
http://dx.doi.org/10.1039/d0ra07093a